Online Resources. PowerPoint presentation by S. Rengasamy: Adopting Asset Mapping in an Urban Ward in Madurai City. (Tamil Nadu, India). Assets-Oriented Community Assessment.Patricia A. Sharpe, Mary R. Greaney, Peter …“Anagoo jiifna ayan ku kacnay qaylo dhaan, saacaddu waxa ay ahayd qiyaastii, toddobo saac - 1 dii saqda dhexe," ayay tiri Sahro. "waa soo barakacnay, …When Chicago cops joined the KKK 55 years ago, the department moved quickly to fire them. By Dan Mihalopoulos | WBEZ and Tom Schuba. Oct 23, 2023, …This event has passed. KU Winter Webinar Series: “Frequency-domain methods in sliding mode control” by Dr. Igor Boiko. January 11, 2021 @ 2:00 ...By expressing and purifying each domain of Mt-LigD, in vitro work revealed the ability of the PolDom and LigDom to function independently and identified the PolDom as the Mt-Ku-binding domain (8,15). Mt-Ku therefore binds to DNA termini and is believed to recruit Mt-LigD through the PolDom . Mt-Ku also stimulates the activity of all three ...① ブラウザを起動します。 ② 「MySoftbank」にアクセスします。 ③ 「携帯電話番号」「「パスワード」を入力しログインします。 ④ 「SMS/MMS」を設定します。Nonhomologous end-joining is another DNA repair mechanism that resolves DSBs. Since it relies on no sequence homology or short overhangs at DSBs, it is an error-prone process. Unlike HRR, which is active in the S and G 2 phases, NHEJ is active in all phases of cell cycle, but is most important in the G 1 phase.Abstract. The DNA-dependent protein kinase (DNA-PK), which comprises the KU heterodimer and a catalytic subunit (DNA-PKcs), is a classical non-homologous end-joining (cNHEJ) factor 1. KU binds to DNA ends, initiates cNHEJ, and recruits and activates DNA-PKcs. KU also binds to RNA, but the relevance of this interaction in mammals is unclear. The N-terminal α/β domain of each Ku subunit is a divergent member of the von Willebrand factor A (vWA) family of domains [], composed of a six-stranded β-sheet …WiFi. Wireless net access You'll find wireless network connections everywhere at the Library. You can choose to log on to KB-net, the Royal Library's net, or the wireless net of University of Copenhagen, Eduroam. The different proteins are expressed with GST (grey box) in N-terminal position, a WAP domain (W), a follistatin/Kazal domain (F/K), an Igc2 domain, two BPTI/kunitz domains (Ku 1 and Ku 2), and a netrin domain (NTR). The domains of GASP-1 and GASP-2 are represented by yellow or green boxes, respectively.Ew peyva hemwate ya domainê ye, û di çerçova torên de, domain qala girêdana malpera weya li ser Internetnternetê dike, ango ew navê malpera we ye ku mêvanek dinivîse da ku rûpela we ji hev cihê bike û bikaribe gihîştina wê, wek www.domain.com, ku peyva domain navê malpera we diyar dike.Apr 15, 2021 · The N-terminal α/β domain of each Ku subunit is a divergent member of the von Willebrand factor A (vWA) family of domains , composed of a six-stranded β-sheet in a Rossman fold . Disrupting the vWA domain in yeast Ku70/80 has been found to impair DNA repair and telomere regulation . Although the amino edge of the vWA domain lies proximal to ... Cross Domain Enterprise Service (CDES) Cyber Sam; Defense Collaboration Services (DCS) DevSecOps Operational Container Scanning; ... CAE-PoS KU Alignment Summary Table 36.77 KB 16 Jun 2021. CAE-CD KU Mapping to NICE Framework Title Size Updated; CAE KU Mapping to NICE FW 2.0 180.51 KB ...Antibodies are heavy (~150 kDa) proteins of about 10 nm in size, arranged in three globular regions that roughly form a Y shape.. In humans and most other mammals, an antibody unit consists of four polypeptide chains; two identical heavy chains and two identical light chains connected by disulfide bonds. Each chain is a series of domains: somewhat similar …Sep 2, 2013 · I want to register a new domain names with .KU (KURDISTAN) extension There's no such country (recognised) so you can't as there's no actual ccTLD .KU (and alt-roots dont count) Rob Golding Astutium Ltd - UK based ICANN Accredited Domain Registrar - proud to accept BitCoins WiFi. Wireless net access You'll find wireless network connections everywhere at the Library. You can choose to log on to KB-net, the Royal Library's net, or the wireless net of University of Copenhagen, Eduroam. To use the NetIQ app you need to install and register it on mfa.ku.dk. - Install and register the app. MitID To use MitID you must have a Danish social security number and MitID. - How to log in with MitID. USB security key / Yubikey To use a USB security key / Yubikey, you must first order and register it.- Students: USB security key instructions.Men&Women ku-to. 埼玉県 さいたま市南区 南浦和2-14-11. 南浦和駅 徒歩 6分. ku-to+ ... ※ドメイン指定受信の解除を予めして下さい。 ↓ ○担当者と面接 ↓ ○採用決定KU IT does not Support the Use of www Domains for KU Hosted Websites Domain names containing www are not supported for KU websites. They are a poor choice for search engine optimization (SEO), are unnecessarily verbose, present additional security challenges, and increase IT costs.About eduroam. eduroam is based on the most secure encryption and authentication standards available. Its security by far exceeds typical commercial hotspots. Find out about eduroam security here. Locations & Participants.myKU is a digital hub for students, faculty, and staff to access services and find resources. myKU enhances the overall KU student digital experience from admission through graduation. By streamlining processes and creating a holistic digital student experience, myKU connects students to important systems, people, and services in a personalized ... To use the NetIQ app you need to install and register it on mfa.ku.dk. - Install and register the app. MitID To use MitID you must have a Danish social security number and MitID. - How to log in with MitID. USB security key / Yubikey To use a USB security key / Yubikey, you must first order and register it.- Students: USB security key instructions. About eduroam. eduroam is based on the most secure encryption and authentication standards available. Its security by far exceeds typical commercial hotspots. Find out about eduroam security here. Locations & Participants.A country code top-level domain (ccTLD) is an Internet top-level domain generally used or reserved for a country, sovereign state, or dependent territory identified with a country code.All ASCII ccTLD identifiers are two letters long, and all two-letter top-level domains are ccTLDs.. In 2018, the Internet Assigned Numbers Authority (IANA) began implementing …'Tracked by the Police is a 1927 silent film produced and distributed by the Warner Bros. with a story written by Darryl Zanuck. It stars dog actor Rin Tin T...WiFi. Wireless net access You'll find wireless network connections everywhere at the Library. You can choose to log on to KB-net, the Royal Library's net, or the wireless net of University of Copenhagen, Eduroam. The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1. Nat Commun 13:5063 (2022). PubMed: 36030235; Guo Z et al. LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma. Cell Death Dis 12:69 (2021). In this article. The PowerShell module named ADSyncConfig.psm1 was introduced with build 1.1.880.0 (released in August 2018) that includes a collection of cmdlets to help you configure the correct Active Directory permissions for your Microsoft Entra Connect deployment.. Overview. The following PowerShell cmdlets can be used to …Enter your Online ID & Password Online ID: Password: Password Reset | Change password | Set up your Online ID For security reasons, please Log Out and Exit your web browser when you are done accessing services that require authentication! Or log in with: Delegate Login KUMC LoginMasih banyak lagi keunggulan dan keuntungan kenapa kamu harus memiliki domain di IDwebhost. Tenang saja, buat kamu yang pemula akan diarahkan dan dimudahkan dalam memilih domain yang tepat untuk website. Segera cek domain murah terbaikmu hanya di IDwebhost. Cek domain terbaik kamu di IDwebhost secara GRATIS. Temukan beragam pilihan nama domain ...Since KDP Select / KU is an Amazon specific program, we also suggest contacting Amazon support to clarify their guidelines. We take some extra precautions while promoting books which are enrolled in KU to better adhere to Amazon's guidelines. We ensure your book does NOT appear in the public domain on BookSirens. For example, your BookSirens ...In eukaryotes, Ku is a heterodimer comprised of two subunits, Ku70 and Ku80, that is best characterized for its central role as the initial DNA end binding factor in the "classical" non-homologous end joining (C-NHEJ) pathway, the main DNA double-strand break (DSB) repair pathway in mammals. Ku binds double-stranded DNA ends with high affinity ... Public Domain Books Welcome to Authorama.com, featuring completely free books from a variety of different authors, collected here for you to read online or offline. The books may have been published before, but not in this form , which I …Kindle Unlimited (KU) is a subscription program where customers can read Kindle eBooks and keep them as long as they want, for a monthly subscription fee. Customers don’t have to be Amazon Prime members to enroll in Kindle Unlimited (KU). When you enroll in KDP Select, your Kindle eBook is automatically included in Kindle Unlimited (KU).Your …Description —. KU Anywhere allows secure access to resources on the KU network, such as a departmental file server, from a computer that is not connected to the KU's network but is connected to the internet. KU Anywhere allows faculty and staff to access needed resources when traveling or working remotely.Description — KU IT provides Wi-Fi (wireless) service for anyone needing internet access while on campus. You can connect to KU Wi-Fi networks by selecting the appropriate wireless network on your computer or mobile device. KU Students, Faculty and StaffThe folded domain in CTR (aa 595–706) is docked onto MH3 (aa 1700–1830), 65 Å away from the bulk of Ku, by a small interface of both hydrophobic and polar nature. In addition, a short helix of Ku80 (aa 548–555) is tucked between the 5 th and 6 th helical repeats of NH1 adjacent to the bridge and pillar of Ku70 ( Figure 4 C).Resolves domains from decentralized blockchain name systems using BDNS public web API. Currently supported TLDs are: .bit (Namecoin), .lib .bazar .coin .emc …If a is the lattice constant, then the exchange energy penalty per unit area of the 180º Bloch wall is: ex E total BW ex 2 2 a2 JS a2 N From this expression it looks like: N ex BW 0, i.e. it is energetically advantageous to have infinitely thick domain walls, which means that there will be no domains but just randomlyDomain history. It seems ku.edu.kw has only been registered once and was never abandoned or has never expired. Rating by Quantcast. Established in 2006, the technology company Quantcast provides audience measurements and an opportunity for advertising in real time. In addition to that, the American company ensures public access to all sorts of ...Men&Women ku-to. 埼玉県 さいたま市南区 南浦和2-14-11. 南浦和駅 徒歩 6分. ku-to+ ... ※ドメイン指定受信の解除を予めして下さい。 ↓ ○担当者と面接 ↓ ○採用決定Ku domain-containing protein InterPro annotation. Organism names. Organism. Sus scrofa (Pig) Imported. Taxonomic identifier. 9823 NCBI. Taxonomic lineage.Feb 16, 2021 · The samples were interpolated to keep a constant sampling rate of 100 Hz. The arrangement of information is the same as above. 3.Time_domain_subsamples.zip 20750 subsamples extracted from the 1945 collected samples provided in a single .csv file. Each of them contains 3 seconds of non-overlapping data of the corresponding activity. Identification of prokaryotic Ku homologs allowed the dissection of the Ku protein sequences into three distinct domains, the Ku core that is conserved in eukaryotes and prokaryotes, a derived von Willebrand A domain that is fused to the amino terminus of the core in eukaryotic Ku proteins, and the newly recognized helix–extension–helix ...KU IT provides Wi-Fi (wireless) service for anyone needing internet access while on campus. You can connect to KU Wi-Fi networks by selecting the appropriate wireless …As a business owner, you know that having an online presence is crucial for success in today’s digital age. One of the first steps in establishing your online brand is choosing a domain name.Customer reviews and Q&As. Recombinant Human Ku70 protein is a Wheat germ Full length protein 1 to 609 aa range and validated in WB, ELISA, SDS-PAGE.The version of the HEH domain present in eukaryotic Ku proteins represents the previously described DNA-binding domain called SAP. The Ku homolog from S. coelicolor contains a distinct version of the HEH domain that belongs to a previously unnoticed family of nucleic-acid-binding domains, which also includes HEH domains from the bacterial ...This model cannot be explicitly described in terms of time derivatives, but is expressed directly in terms of complex numbers in the frequency domain. The force in the spring is assumed to be out of phase with the displacement, resulting in a complex-valued stiffness. The resulting eigenvalue equation becomes. where is the loss factor.Signal peptides, KU domains and regions of compositional complexity are represented in red, green and pink, respectively. (B) The secondary structure of protein motifs of SsTFPI-2 predicted by PBIL. The alpha helix region is shown in blue, the extended strand region is shown in red, and the random coil region is shown in yellow. ...Academic Departments. KU's academic and clinical departments offer a range of study options in locations throughout Kansas City, Wichita and Salina in addition to opportunities at centers and institutes affiliated with KU throughout the nation. The University of Kansas School of Medicine offers a range of academic departments divided into Basic ...Ensure your website is up and running with our 99.9% uptime guarantee. Hostinger proved itself a reliable web hosting service. In fact, our test site didn't go down once during the 14-day observation period. Plans include SSL certificates and all servers have an advanced security module to protect your data.Create your own website without any programming knowledge. Create a Website. Webhosting. Concentrate fully on your project! Performance and security included. …While Ku in eukaryotes is often a multi-domain protein functioning in DNA repair of physiological and pathological DNA double-stranded breaks, Ku in prokaryotes is a single-domain protein ...General notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here.KU N terminal, KU 70/80 Beta barrel domain, KU C terminal, and various other domain’s sequence lengths were tabulated using Microsoft Excel-2010 (Supp. Tables 1 & 2). Various domain architectures of some primary organisms representing their respective phylum were drawn. Domain / Hosting / IP Registration Form Contact Information* Technical Contact Full Name Contact Number Email Address Administrative Contact Full Name Contact Number …Problem 4.4 When the input to an LTI system is the unit step function u(t), the output is r(t) = 0 if t < 0 t if 0 ≤t ≤1 1 if t > 1.Automatic Group: Auto CC/BCC: Easily set up CC or BCC rules for all sending emails in Outlook. Auto Forward: Easily set up rules for automatically forwarding all receiving emails to specific recipients. Auto Reply: Easily set up Auto Reply rules for out of office for one or multiple email accounts at the same time with customized subject and body. Block …Feb 18, 2021 · The folded domain in CTR (aa 595–706) is docked onto MH3 (aa 1700–1830), 65 Å away from the bulk of Ku, by a small interface of both hydrophobic and polar nature. In addition, a short helix of Ku80 (aa 548–555) is tucked between the 5 th and 6 th helical repeats of NH1 adjacent to the bridge and pillar of Ku70 ( Figure 4 C). Background and publication. According to his own account, Sax Rohmer decided to start the Dr. Fu Manchu series after his Ouija board spelled out C-H-I-N-A-M-A-N when he asked what would make his fortune. Clive Bloom argues that the portrait of Fu Manchu was based on the popular music hall magician Chung Ling Soo, "a white man in costume who had …Listen to KU LO SA with Camila Cabello on streaming platforms: https://oxlade.lnk.to/kulosaremixConnect with Oxlade: Instagram: https://www.instagram.com/oxl...Along with his colleague Mary Boone, he published the framework in the November 2007 issue of the Harvard Business Review. The Cynefin framework (Figure 1 below) is a problem-solving tool that helps you put situations into five "domains" defined by cause-and-effect relationships. This helps you assess your situation more accurately and respond ...Korea University (KU, Korean: 고려대학교; Hanja: 高麗大學校; RR: Goryeo Daehakgyo) is a private research university in Seoul, South Korea, established in 1905.The university is included as one of the SKY Universities, a popular acronym referring to Korea's three most prestigious universities. Korea University is named after Goguryeo.. The student body …yoroshiku.onegai.shim.earth. nasa.so. otsu.careMen&Women ku-to. 埼玉県 さいたま市南区 南浦和2-14-11. 南浦和駅 徒歩 6分. ku-to+ ... ※ドメイン指定受信の解除を予めして下さい。 ↓ ○担当者と面接 ↓ ○採用決定While Ku in eukaryotes is often a multi-domain protein functioning in DNA repair of physiological and pathological DNA double-stranded breaks, Ku in prokaryotes is a single-domain protein ...Fundamental operation A block diagram of a PID controller in a feedback loop. r(t) is the desired process variable (PV) or setpoint (SP), and y(t) is the measured PV.. The distinguishing feature of the PID controller is the ability to use the three control terms of proportional, integral and derivative influence on the controller output to apply accurate …( = kU ) domain, S o ( m, ). This source function then serves as a bottom boundary condition for an inte-rior wave eld having both upward ( E +) and downward ( E ) propagating components, Section 8. Evaluating the vertical evolution of the wave eld re-quires de ning the relative eects of vertical propaga-Moodle puts the power of eLearning in your hands. At Moodle, our mission is to empower educators to improve our world with our open source eLearning software. Flexible, secure, and customisable for any online teaching or training initiative, Moodle gives you the freedom to create an eLearning platform that best meets your needs.KU Leuven-staff and -students are advised to use the CAT-tool to automatically configure the wireless networks campusroam and eduroam. Download the tool from cat.eduroam.org, or scan the QR-code to the right. The tool does the complete configuration from scratch or adjusts existing configurations for pc, smartphone and tablet.The closest relative of the Ku β-barrel domain is the SPOC domain (Andreeva et al., 2004; Ariyoshi and Schwabe, 2003), which, lacks the bridge module and provides a model for the structural prototype of the Ku barrel prior to the Zn-ribbon insertion. However, SPOC is restricted to eukaryotes and is thus unlikely to be the precursor of the Ku ...Because many different versions of Android are in use, the instructions that follow are intended to provide a general guide how to configure your Wi-Fi settings. Your own device's exact appearance may differ. The General Setup steps work for Chromebook. General Setup On the list of available networks, tap eduroam. Enter or select the following in the …The different proteins are expressed with GST (grey box) in N-terminal position, a WAP domain (W), a follistatin/Kazal domain (F/K), an Igc2 domain, two BPTI/kunitz domains (Ku 1 and Ku 2), and a netrin domain (NTR). The domains of GASP-1 and GASP-2 are represented by yellow or green boxes, respectively.KU N terminal, KU 70/80 Beta barrel domain, KU C terminal, and various other domain’s sequence lengths were tabulated using Microsoft Excel-2010 (Supp. Tables 1 & 2). Various domain architectures of some primary organisms representing their respective phylum were drawn.In today’s digital age, having a strong online presence is essential for businesses and individuals alike. One of the key elements of building this presence is securing the right domain name.Description —. KU offers three options for web/video conferencing: Skype for Business is best for voice and video calls with KU faculty and staff. Microsoft Teams is best for online meetings with department work teams and KU colleagues. Zoom is best for conference room video conferencing and online meetings with external partners.Abacadabra. See All Plugins. Your domain registration questions, answered. How does getting a domain work? There are two pieces to this equation. First, there are domain …Lenovo IdeaPad Slim AMD 3 Ryzen 5 5500U 15.6" (39.62cm) IPS FHD Laptop (16GB/512GB SSD/Win 11/Office 2021/2 Year Warranty/Alexa Built-in/3 Month Game …DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a member of the phosphatidylinositol 3-kinase related kinase family, which can phosphorylate more than 700 substrates. As the core enzyme, DNA-PKcs forms the active DNA-PK holoenzyme with the Ku80/Ku70 heterodimer to play crucial roles in cellular DNA damage response (DDR). Once DNA double strand breaks (DSBs) occur in the cells, DNA ...DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a member of the phosphatidylinositol 3-kinase related kinase family, which can phosphorylate more than 700 substrates. As the core enzyme, DNA-PKcs forms the active DNA-PK holoenzyme with the Ku80/Ku70 heterodimer to play crucial roles in cellular DNA damage response (DDR). Once DNA double strand breaks (DSBs) occur in the cells, DNA ...Welcome to Nominet - Official registry for .UK domain names. Discover our domain name registration services, Cyber solutions and WHOIS lookup toolThe Ku core domain is generally very close to the N-terminus as 92.9% of Ku proteins have an N-terminal extension of 5 residues or less (Figure (Figure1D 1D and Supplementary Table S1). Extending the Ku core domain, all prokaryotic Ku proteins display a C-terminal region ranging from 19 to 173 residues (average 59) in length.KU IT includes a 24/7 enterprise data center and many knowledgeable staff providing KU with expertise in server and desktop support, application support, software development, IT security, networking, as well as customer support and project management. Working together, our staff deliver technology services you use at KU. Our Values. Integrity ...When it comes to building a website or an online business, one of the most crucial decisions you’ll make is choosing a domain name. Your domain name serves as your online identity, so it’s important to choose one that’s memorable, easy to s...
Domain / Hosting / IP Registration Form Contact Information* Technical Contact Full Name Contact Number Email Address Administrative Contact Full Name Contact Number …. Clamble likes
Eminent Domain. Friday, November 3, 1905. More recent students and alumni know it as Lippincott Hall, the University’s sole Greco-Roman style structure on Jayhawk Boulevard named after KU’s fourth chancellor. This nomenclature, however, is a fairly recent innovation, for as anyone who attended KU before the late 1970s could tell you, the ...At KU Leuven and UZ Leuven, our researchers and students work together to develop new insights and sustainable innovations. With over 200 charities, we drive progress in education and research, healthcare and culture, at home and far beyond. Our aim is to help society face current and future challenges, an endeavour in which you can support us.ku.edu. This Registry database contains ONLY .EDU domains. The data in the EDUCAUSE Whois database is provided by EDUCAUSE for information purposes in order to assist in the process of obtaining information about or related to .edu domain registration records.The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1. Nat Commun 13:5063 (2022). PubMed: 36030235; Guo Z et al. LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma. Cell Death Dis 12:69 (2021).① ブラウザを起動します。 ② 「MySoftbank」にアクセスします。 ③ 「携帯電話番号」「「パスワード」を入力しログインします。 ④ 「SMS/MMS」を設定します。Kansas City, Mo. — Big 12 Conference Commissioner Brett Yormark preemptively declined comment on his league’s hottest topic, expansion — other than to say that nothing else was imminent in ...Abstract. The DNA-dependent protein kinase (DNA-PK), which comprises the KU heterodimer and a catalytic subunit (DNA-PKcs), is a classical non-homologous end-joining (cNHEJ) factor 1. KU binds to DNA ends, initiates cNHEJ, and recruits and activates DNA-PKcs. KU also binds to RNA, but the relevance of this interaction in mammals is unclear.streptococcus, (genus Streptococcus), group of spheroidal bacteria belonging to the family Streptococcaceae. The term streptococcus (“twisted berry”) refers to the bacteria’s characteristic grouping in chains that resemble a string of beads. Streptococci are microbiologically characterized as gram-positive and nonmotile. Streptococcus contains …2 hours ago · Kansas families are frightened as they see their individual rights being questioned. Taking property away by eminent domain has people worried.” Crossland-Macha, a former Kansas Republican Party officer, was founder of Kansas Senior Consumer Alliance, a 2014 group that campaigned against applying renwable energy standards to Kansas utilities. Description —. KU offers three options for web/video conferencing: Skype for Business is best for voice and video calls with KU faculty and staff. Microsoft Teams is best for online meetings with department work teams and KU colleagues. Zoom is best for conference room video conferencing and online meetings with external partners.eduroam. The University of Kansas is a member of eduroam, a global consortium of thousands of institutions offering quick and easy access to local Wi-Fi networks in more …Internet domain suffixes. Originally developed at the ISI (Information Sciences Institute), founded by Keith Uncapher, Internet domain suffixes help identify domain names on the Internet. For example, with the "computerhope.com" domain, ".com" is the domain suffix. Below are Internet domain suffixes, aka TLD ( top-level domains ), and their ...The Ku70 SAP domain is present in both crystals of Ku free (apo-Ku) and Ku complex, but it is only visible in the crystal structure of apo-Ku where it is in contact with the Ku80 α/β domain. Using electron microscopy, Rivera-Calzada mapped these C -terminal regions and their conformational changes after DNA and DNA-PKcs binding on maps at low ...The N-terminal α/β domain of each Ku subunit is a divergent member of the von Willebrand factor A (vWA) family of domains [], composed of a six-stranded β-sheet ….